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Autoantibodies against cytochrome P450s in sera of children treated with immunosuppressive drugs
Treatment with the immunosuppressive drugs cyclosporin and tacrolimus, the mainstays of anti-graft rejection and autoimmune disease therapy, is limited by their hepato-and nephrotoxicity. The metabolic conversion of these compounds to more easily excretable products is catalysed mainly by hepatic cy...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1906342/ https://ncbi.nlm.nih.gov/pubmed/11876753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01754.x |
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