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Conditional human immunodeficiency virus type 1 protease mutants show no role for the viral protease early in virus replication.

The human immunodeficiency virus type 1 protease plays a critical role in the proteolytic processing of precursor polyproteins during virion maturation. Contradictory evidence has been obtained for a possible role for the protease early after infection, i.e., during DNA synthesis and/or integration....

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Kaplan, A H, Manchester, M, Smith, T, Yang, Y L, Swanstrom, R
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190600/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8709202/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.9.5840-5844.1996
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