Epitope focus, clonal composition and Th1 phenotype of the human CD4 response to the secretory mycobacterial antigen Ag85

Lymphoproliferation of healthy donors was tested against mycobacterial antigens (PPD, Ag85, Ag85 peptides). All PPD responders recognized the secretory antigen Ag85 and the peptide specificity for Ag85B was defined. Peptide 91–108 was recognized by 85% of donors. In addition, all CD4 T cell lines ge...

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Bibliografiske detaljer
Main Authors: Valle, M T, Megiovanni, A M, Merlo, A, Li Pira, G, Bottone, L, Angelini, G, Bracci, L, Lozzi, L, Huygen, K, Manca, F
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2001
Fag:
Immunity to Infection
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905982/
https://ncbi.nlm.nih.gov/pubmed/11207652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01450.x
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