Epitope focus, clonal composition and Th1 phenotype of the human CD4 response to the secretory mycobacterial antigen Ag85

Lymphoproliferation of healthy donors was tested against mycobacterial antigens (PPD, Ag85, Ag85 peptides). All PPD responders recognized the secretory antigen Ag85 and the peptide specificity for Ag85B was defined. Peptide 91–108 was recognized by 85% of donors. In addition, all CD4 T cell lines ge...

Full description

Saved in:
Bibliographic Details
Main Authors: Valle, M T, Megiovanni, A M, Merlo, A, Li Pira, G, Bottone, L, Angelini, G, Bracci, L, Lozzi, L, Huygen, K, Manca, F
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2001
Subjects:
Immunity to Infection
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905982/
https://ncbi.nlm.nih.gov/pubmed/11207652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01450.x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items