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Primate TNF Promoters Reveal Markers of Phylogeny and Evolution of Innate Immunity
BACKGROUND: Tumor necrosis factor (TNF) is a critical cytokine in the immune response whose transcriptional activation is controlled by a proximal promoter region that is highly conserved in mammals and, in particular, primates. Specific single nucleotide polymorphisms (SNPs) upstream of the proxima...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1905939/ https://ncbi.nlm.nih.gov/pubmed/17637837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000621 |
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