Induction of CD95 ligand expression on T lymphocytes and B lymphocytes and its contribution to apoptosis of CD95-up-regulated CD4(+) T lymphocytes in macaques by infection with a pathogenic simian/human immunodeficiency virus

Using an established SIV/HIV-C2/1-infected cynomolgus monkey model displaying stable CD4(+) T cell depletion, the kinetics of apoptosis and the levels of expression of CD95 membrane-associated CD95L on lymphocytes were investigated to test the involvement of the CD95/CD95L system in CD4(+) T lymphoc...

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Autors principals: Sasaki, Y, Ami, Y, Nakasone, T, Shinohara, K, Takahashi, E, Ando, S, Someya, K, Suzaki, Y, Honda, M
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2000
Matèries:
Immunity to Infection
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905812/
https://ncbi.nlm.nih.gov/pubmed/11122244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01327.x
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