In vitro T lymphocyte responses to proteinase 3 (PR3) and linear peptides of PR3 in patients with Wegener's granulomatosis (WG)

T cell-mediated immunity is thought to play an important role in the pathogenesis of WG. In previous studies a minority of WG patients as well as some healthy controls showed in vitro proliferation of their peripheral blood mononuclear cells (PBMC) to PR3, the main autoantigen in WG. The relevant pe...

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Detalhes bibliográficos
Main Authors: Van Der Geld, Y M, Huitema, M G, Franssen, C F M, Van Der Zee, R, Limburg, P C, Kallenberg, C G M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Vasculitis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905800/
https://ncbi.nlm.nih.gov/pubmed/11122262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01415.x
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