Interference of PR3-ANCA with the enzymatic activity of PR3: differences in patients during active disease or remission of Wegener's granulomatosis

Anti-neutrophil cytoplasmic antibodies (ANCA) against proteinase 3 (PR3) are strongly associated with Wegener's granulomatosis (WG) and are thought to be involved in its pathogenesis. Levels of PR3-ANCA do not always correspond to clinical disease activity. To investigate the relationship betwe...

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Detalhes bibliográficos
Main Authors: Van Der Geld, Y M, Tool, A T J, Videler, J, De Haas, M, Cohen Tervaert, J W, Stegeman, C A, Limburg, P C, Kallenberg, C G M, Roos, D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Clinical Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906460/
https://ncbi.nlm.nih.gov/pubmed/12197900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01926.x
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