Treatment with a monoclonal antibody to IL-8 attenuates the pleocytosis in experimental pneumococcal meningitis in rabbits when given intravenously, but not intracisternally

The role of interleukin (IL)-8 as mediator in the recruitment of leucocytes into the CSF was investigated during experimental pneumococcal meningitis. Rabbits were inoculated intracisternally with approximately 10(6) CFU Streptococcus pneumoniae, and treated (i) intravenously with 5 mg of a monoclon...

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Détails bibliographiques
Auteurs principaux: Østergaard, C, Yieng-Kow, R V, Larsen, C G, Mukaida, N, Matsushima, K, Benfield, T, Frimodt-Møller, N, Espersen, F, Kharazmi, A, Lundgren, J D
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2000
Sujets:
Rheumatic Disease
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905781/
https://ncbi.nlm.nih.gov/pubmed/11091276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01357.x
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