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Antigen-specific T cell responses in human peripheral blood leucocyte (hu-PBL)–mouse chimera conditioned with radiation and an antibody directed against the mouse IL-2 receptor β-chain
A weakness of the hu-PBL–SCID model for the study of human immune functions is the appearance of anergy and the consequent loss of T cell function. We demonstrate here that human T cells retain normal functions during the early stage of chimerism. At 1 and 2 weeks post-engraftment, T cells isolated...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Blackwell Science Inc
2000
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1905761/ https://ncbi.nlm.nih.gov/pubmed/11012627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01340.x |
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