Limitations of the semisynthetic library approach for obtaining human monoclonal autoantibodies to the thyrotropin receptor of Graves' disease

Graves' disease (GD) is characterized by the presence of autoantibodies against the TSH-receptor (TSH-R) which are pathogenic and, upon binding to the receptor, trigger intracellular signal transduction. The autoantibodies are oligoclonal and as they are responsible for disease activity, their...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Van Der Heijden, J H W, De Bruin, T W A, Glaudemans, K A F M, De Kruif, J, Banga, J P, Logtenberg, T
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905415/
https://ncbi.nlm.nih.gov/pubmed/10540180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.01042.x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados