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The T cell receptor repertoire of CD8(+)CD28(−) T lymphocytes is dominated by expanded clones that persist over time

The costimulatory molecule CD28 is expressed on almost all CD4(+) T cells, but on only a portion of CD8(+) T cells in healthy human adults. αβ T cells may thus be divided into three phenotypically and functionally different subsets: CD4(+), CD8(+)CD28(+) and CD8(+)CD28(−). Using peripheral blood lym...

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Autori principali: Mugnaini, E N, Egeland, T, Spurkland, A, Brinchmann, J E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905325/
https://ncbi.nlm.nih.gov/pubmed/10444261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00980.x
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