CD8β/CD28 expression defines functionally distinct populations of peripheral blood T lymphocytes

Peripheral blood CD8(+) T lymphocytes generally express the CD8 coreceptor as an αβ heterodimer. On these cells, the CD8β chain is present either at high (CD8β(high)) or low density (CD8β(low)). CD8β(high) cells are CD28(+), whereas CD8β(low) cells are CD28(+) or CD28(–). Therefore, three subpopulat...

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Bibliografiske detaljer
Main Authors: WERWITZKE, S, TIEDE, A, DRESCHER, B E, SCHMIDT, R E, WITTE, T
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2003
Fag:
Basic Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808803/
https://ncbi.nlm.nih.gov/pubmed/12930358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02226.x
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