Human immunodeficiency virus fitness in vivo: calculations based on a single zidovudine resistance mutation at codon 215 of reverse transcriptase.

We monitored a subject newly infected with a zidovudine-resistant human immunodeficiency virus type 1 strain and found that in the absence of drug, the viral population with the resistance-conferring tyrosine (TAC) codon 215 of reverse transcriptase was gradually replaced. By using standard formulas...

Description complète

Détails bibliographiques

Publié dans:	J Virol
Auteurs principaux:	Goudsmit, J, De Ronde, A, Ho, D D, Perelson, A S
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190530/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8764084/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.8.5662-5664.1996
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!