Human immunodeficiency virus fitness in vivo: calculations based on a single zidovudine resistance mutation at codon 215 of reverse transcriptase.

We monitored a subject newly infected with a zidovudine-resistant human immunodeficiency virus type 1 strain and found that in the absence of drug, the viral population with the resistance-conferring tyrosine (TAC) codon 215 of reverse transcriptase was gradually replaced. By using standard formulas...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Goudsmit, J, De Ronde, A, Ho, D D, Perelson, A S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190530/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8764084/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.8.5662-5664.1996
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