N-formyl-methionyl-leucyl-phenylalanine (fMLP) inhibits tumour necrosis factor-alpha (TNF-α) production on lipopolysaccharide (LPS)-stimulated human neutrophils

During Gram-negative infections bacterial components, such as LPS and formylated peptides, exert profound physiological effects on polymorphonuclear neutrophils (PMN) resulting in increased neutrophil effector activities, including the generation of oxidative metabolites, degranulation, phagocytosis...

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Hlavní autoři: Vulcano, M, Alves Rosa, M F, Minnucci, F S, Cherñavsky, A C, Isturiz, M A
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 1998
Témata:
Immunity to Infection
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905013/
https://ncbi.nlm.nih.gov/pubmed/9697981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00631.x
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