N-formyl-methionyl-leucyl-phenylalanine (fMLP) inhibits tumour necrosis factor-alpha (TNF-α) production on lipopolysaccharide (LPS)-stimulated human neutrophils

During Gram-negative infections bacterial components, such as LPS and formylated peptides, exert profound physiological effects on polymorphonuclear neutrophils (PMN) resulting in increased neutrophil effector activities, including the generation of oxidative metabolites, degranulation, phagocytosis...

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Detalhes bibliográficos
Main Authors: Vulcano, M, Alves Rosa, M F, Minnucci, F S, Cherñavsky, A C, Isturiz, M A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1998
Assuntos:
Immunity to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905013/
https://ncbi.nlm.nih.gov/pubmed/9697981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00631.x
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