N-formyl-methionyl-leucyl-phenylalanine (fMLP) inhibits tumour necrosis factor-alpha (TNF-α) production on lipopolysaccharide (LPS)-stimulated human neutrophils

During Gram-negative infections bacterial components, such as LPS and formylated peptides, exert profound physiological effects on polymorphonuclear neutrophils (PMN) resulting in increased neutrophil effector activities, including the generation of oxidative metabolites, degranulation, phagocytosis...

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Main Authors: Vulcano, M, Alves Rosa, M F, Minnucci, F S, Cherñavsky, A C, Isturiz, M A
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 1998
主題:
Immunity to Infection
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905013/
https://ncbi.nlm.nih.gov/pubmed/9697981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00631.x
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