N-formyl-methionyl-leucyl-phenylalanine (fMLP) inhibits tumour necrosis factor-alpha (TNF-α) production on lipopolysaccharide (LPS)-stimulated human neutrophils

During Gram-negative infections bacterial components, such as LPS and formylated peptides, exert profound physiological effects on polymorphonuclear neutrophils (PMN) resulting in increased neutrophil effector activities, including the generation of oxidative metabolites, degranulation, phagocytosis...

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Bibliografiske detaljer
Main Authors: Vulcano, M, Alves Rosa, M F, Minnucci, F S, Cherñavsky, A C, Isturiz, M A
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 1998
Fag:
Immunity to Infection
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905013/
https://ncbi.nlm.nih.gov/pubmed/9697981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00631.x
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