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vif-negative human immunodeficiency virus type 1 persistently replicates in primary macrophages, producing attenuated progeny virus.

The vif gene of human immunodeficiency virus type 1 (HIV-1) is required for efficient infection of primary T lymphocytes. In this study, we investigated in detail the role of vif in productive infection of primary monocyte-derived macrophages (MDM). Viruses carrying missense or deletion mutations in...

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Bibliografische gegevens
Hoofdauteurs: Chowdhury, I H, Chao, W, Potash, M J, Sova, P, Gendelman, H E, Volsky, D J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC190491/
https://ncbi.nlm.nih.gov/pubmed/8764044
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