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Peptide inhibitors of HIV-1 protease and viral infection of peripheral blood lymphocytes based on HIV-1 Vif

We recently reported that HIV-1 Vif (virion infectivity factor) inhibits HIV-1 protease in vitro and in bacteria, suggesting that it may serve as the basis for the design of new protease inhibitors and treatment for HIV-1 infection. To evaluate this possibility, we synthesized peptide derivatives fr...

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Detalhes bibliográficos
Main Authors: Potash, Mary Jane, Bentsman, Galina, Muir, Tom, Krachmarov, Chavdar, Sova, Pavel, Volsky, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24935/
https://ncbi.nlm.nih.gov/pubmed/9811892
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