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vif-negative human immunodeficiency virus type 1 persistently replicates in primary macrophages, producing attenuated progeny virus.

The vif gene of human immunodeficiency virus type 1 (HIV-1) is required for efficient infection of primary T lymphocytes. In this study, we investigated in detail the role of vif in productive infection of primary monocyte-derived macrophages (MDM). Viruses carrying missense or deletion mutations in...

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Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Chowdhury, I H, Chao, W, Potash, M J, Sova, P, Gendelman, H E, Volsky, D J
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1996
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190491/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8764044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.8.5336-5345.1996
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