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B cell-deficient mice do not develop type II collagen-induced arthritis (CIA)
To investigate the role of B cells in the development of CIA, a model for rheumatoid arthritis, we investigated susceptibility to CIA in mice lacking B cells due to the deletion of the IgM heavy chain gene (μMT). The μMT deletion was backcrossed into two different CIA-susceptible strains, B10.Q and...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Blackwell Science Inc
1998
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1904879/ https://ncbi.nlm.nih.gov/pubmed/9528892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00529.x |
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