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Oestrogen induced suppression of collagen arthritis: I. Long term oestradiol treatment of DBA/1 mice reduces severity and incidence of arthritis and decreases the anti type II collagen immune response.

Experimental animal models can be used to help understand how oestrogen modulates autoimmune arthritis. We have previously shown that castration of female DBA/1 mice exaggerates arthritis induced with type II collagen. This report shows that treatment of castrated DBA/1 mice with low doses (0.2 micr...

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Bibliografiske detaljer
Main Authors: Holmdahl, R, Jansson, L, Meyerson, B, Klareskog, L
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1542083/
https://ncbi.nlm.nih.gov/pubmed/3501349
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