Cyclosporine A-resistant human immunodeficiency virus type 1 mutants demonstrate that Gag encodes the functional target of cyclophilin A.

Documenti analoghi

• Spontaneous mutations in the human immunodeficiency virus type 1 gag gene that affect viral replication in the presence of cyclosporins.
  di: Aberham, C, et al.
  Pubblicazione: (1996)
• Cyclophilin binding to the human immunodeficiency virus type 1 Gag polyprotein is mimicked by an anti-cyclosporine antibody.
  di: Franke, E K, et al.
  Pubblicazione: (1995)
• The hydrophobic pocket of cyclophilin is the binding site for the human immunodeficiency virus type 1 Gag polyprotein.
  di: Braaten, D, et al.
  Pubblicazione: (1997)
• Binding of the human immunodeficiency virus type 1 Gag polyprotein to cyclophilin A is mediated by the central region of capsid and requires Gag dimerization.
  di: Colgan, J, et al.
  Pubblicazione: (1996)
• Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cells
  di: Braaten, Douglas, et al.
  Pubblicazione: (2001)