Binding of the human immunodeficiency virus type 1 Gag polyprotein to cyclophilin A is mediated by the central region of capsid and requires Gag dimerization.

The cellular peptidyl-prolyl isomerase cyclophilin A (CyPA) is incorporated into human immunodeficiency virus type 1 (HIV-1) virions via direct contacts with the HIV-1 Gag polyprotein. Disruption of the Gag-CyPA interaction leads to the production of HIV-1 particles lacking CyPA; these virions are n...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Colgan, J, Yuan, H E, Franke, E K, Luban, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190362/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8676452/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.7.4299-4310.1996
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