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Isolation of human anti-c-erb B-2 Fabs from a lymph node-derived phage display library

An immunoglobulin phage display library constructed from a tumour-associated pericolic lymph node was panned against the extracellular domain of the oncoprotein c-erb B-2. Sixteen independent clones were confirmed as positive binders based on ELISA analysis of soluble Fabs. Nucleotide sequencing dem...

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Detalhes bibliográficos
Main Authors: CLARK, M A, HAWKINS, N J, PAPAIOANNOU, A, FIDDES, R J, WARD, R L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904704/
https://ncbi.nlm.nih.gov/pubmed/9218840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.4161316.x
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