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Polycomb protein Cbx4 promotes SUMO modification of de novo DNA methyltransferase Dnmt3a

The ‘de novo methyltransferase’ Dnmt3a (DNA methyltransferase 3a) has been shown to mediate transcriptional repression. Post-translational modification of Dnmt3a by SUMOylation affects its ability to transcriptionally repress. However, very little is known about how the SUMOylation process is regula...

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Bibliografiske detaljer
Main Authors: Li, Bing, Zhou, Jing, Liu, Peng, Hu, Jialei, Jin, Hong, Shimono, Yohei, Takahashi, Masahide, Xu, Guoliang
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904525/
https://ncbi.nlm.nih.gov/pubmed/17439403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061873
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