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DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer
DNA methylation patterns are established and maintained by three DNA methyltransferases (DNMTs): DNMT1, DNMT3A, and DNMT3B. While essential for development, methylation patterns are frequently disrupted in cancer and contribute directly to carcinogenesis. Recent studies linking polycomb group (PcG)...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745494/ https://ncbi.nlm.nih.gov/pubmed/19723660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0116 |
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