Differential expression and role of p21(cip/waf1 )and p27(kip1 )in TNF-α-induced inhibition of proliferation in human glioma cells

BACKGROUND: The role of TNF-α in affecting the fate of tumors is controversial, while some studies have reported apoptotic or necrotic effects of TNF-α, others provide evidence that endogenous TNF-α promotes growth and development of tumors. Understanding the mechanism(s) of TNF-α mediated growth ar...

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Detalhes bibliográficos
Main Authors: Kumar, Pabbisetty Sudheer, Shiras, Anjali, Das, Gowry, Jagtap, Jayashree C, Prasad, Vandna, Shastry, Padma
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904457/
https://ncbi.nlm.nih.gov/pubmed/17565690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-6-42
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