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Prognostic significance of p21(WAF1/CIP1), p27(Kip1), p53 and E‐cadherin expression in gastric cancer

BACKGROUND: Gastric carcinoma is characterised by numerous genetic and epigenetic alterations that influence cell cycle progression, apoptosis and DNA repair. These alterations include down‐regulation of the cyclin‐dependent kinase (CDK) inhibitors p21(WAF1/CIP1) and p27(Kip1), and mutations of the...

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Main Authors: Gamboa‐Dominguez, Armando, Seidl, Stefan, Reyes‐Gutierrez, Edgardo, Hermannstädter, Christine, Quintanilla‐Martinez, Leticia, Busch, Raymonde, Höfler, Heinz, Fend, Falko, Luber, Birgit
Format: Artigo
Language:Inglês
Published: BMJ Group 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995786/
https://ncbi.nlm.nih.gov/pubmed/17483253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2006.038976
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