Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites

BACKGROUND: The var multigene family encodes PfEMP1, which are expressed on the surface of infected erythrocytes and bind to various host endothelial receptors. Antigenic variation of PfEMP1 plays a key role in malaria pathogenesis, a process partially controlled at the level of var gene transcripti...

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Autors principals: Dahlbäck, Madeleine, Lavstsen, Thomas, Salanti, Ali, Hviid, Lars, Arnot, David E, Theander, Thor G, Nielsen, Morten A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904452/
https://ncbi.nlm.nih.gov/pubmed/17565661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-6-78
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