Baculovirus-Expressed Constructs Induce Immunoglobulin G That Recognizes VAR2CSA on Plasmodium falciparum- Infected Erythrocytes

We raised specific antisera against recombinant VAR2CSA domains produced in Escherichia coli and in insect cells. All were reactive in enzyme-linked immunosorbent assay, but only insect cell-derived constructs induced immunoglobulin G (IgG) that was reactive with native VAR2CSA on the surface of inf...

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Bibliografiske detaljer
Main Authors: Barfod, Lea, Nielsen, Morten A., Turner, Louise, Dahlbäck, Madeleine, Jensen, Anja T. R., Hviid, Lars, Theander, Thor G., Salanti, Ali
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489712/
https://ncbi.nlm.nih.gov/pubmed/16790811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01617-05
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