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Epstein-Barr virus nuclear antigen 2 and latent membrane protein independently transactivate p53 through induction of NF-kappaB activity.

B-cell immortalization by Epstein-Barr virus (EBV) is dependent on permanent control of the cellular processes which normally regulate cell division and apoptosis, functions possessed by p53 in a number of normal cell types. In studies initiated to evaluate relationships between EBV latent genes and...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Chen, W, Cooper, N R
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1996
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190431/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8676521/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.7.4849-4853.1996
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