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Epstein-Barr virus nuclear antigen 2 and latent membrane protein independently transactivate p53 through induction of NF-kappaB activity.

B-cell immortalization by Epstein-Barr virus (EBV) is dependent on permanent control of the cellular processes which normally regulate cell division and apoptosis, functions possessed by p53 in a number of normal cell types. In studies initiated to evaluate relationships between EBV latent genes and...

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Bibliografske podrobnosti
Main Authors: Chen, W, Cooper, N R
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC190431/
https://ncbi.nlm.nih.gov/pubmed/8676521
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