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Functional Cooperation of Epstein-Barr Virus Nuclear Antigen 2 and the Survival Motor Neuron Protein in Transactivation of the Viral LMP1 Promoter

Epstein-Barr virus nuclear antigen 2 (EBNA2) is essential for viral transformation of B cells and transactivates cellular and viral target genes by binding RBPJκ tethered to cognate promoter elements. EBNA2 interacts with the DEAD-box protein DP103 (DDX20/Gemin3), which in turn is complexed to the s...

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Detalhes bibliográficos
Main Authors: Voss, Marc D., Hille, Annette, Barth, Stephanie, Spurk, Andreas, Hennrich, Frank, Holzer, Daniela, Mueller-Lantzsch, Nikolaus, Kremmer, Elisabeth, Grässer, Friedrich A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114764/
https://ncbi.nlm.nih.gov/pubmed/11689659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.23.11781-11790.2001
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