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Increased polymerase fidelity of E89G, a nucleoside analog-resistant variant of human immunodeficiency virus type 1 reverse transcriptase.

Nucleoside analog resistance in human immunodeficiency virus type 1 results from mutations in reverse transcriptase (RT) that allow the enzyme to discriminate against such analogs. To evaluate the possible impact of such mutations on the ability of human immunodeficiency virus RT to selectively inco...

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Udgivet i:J Virol
Principais autores: Drosopoulos, W C, Prasad, V R
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190428/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8676518/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.7.4834-4838.1996
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