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Modulating the Expression of Disease Genes with RNA-Based Therapy

Conventional gene therapy has focused largely on gene replacement in target cells. However, progress from basic research to the clinic has been slow for reasons relating principally to the challenges of heterologous DNA delivery and regulation in vivo. Alternative approaches targeting RNA have the p...

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Detalhes bibliográficos
Main Authors: Wood, Matthew, Yin, Haifang, McClorey, Graham
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904251/
https://ncbi.nlm.nih.gov/pubmed/17604456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030109
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