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Small RNA-Mediated Epigenetic Myostatin Silencing
Myostatin (Mstn) is a secreted growth factor that negatively regulates muscle mass and is therefore a potential pharmacological target for the treatment of muscle wasting disorders such as Duchenne muscular dystrophy. Here we describe a novel Mstn blockade approach in which small interfering RNAs (s...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390243/ https://ncbi.nlm.nih.gov/pubmed/23344003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2012.15 |
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