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The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells
Proteins involved in cholesterol trafficking are known to contribute to the pathogenesis of atherosclerosis and Alzheimer's disease. Allelic variants in the cholesterol transporters apolipoprotein E and ATP-binding cassette protein A1 (ABCA1) have recently been associated with susceptibility to...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1904145/ https://ncbi.nlm.nih.gov/pubmed/17578916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702504104 |
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