Identification of two amino acids in the hemagglutinin glycoprotein of measles virus (MV) that govern hemadsorption, HeLa cell fusion, and CD46 downregulation: phenotypic markers that differentiate vaccine and wild-type MV strains.

We have used site-directed mutagenesis of the hemagglutinin (H) glycoprotein of measles virus (MV) to investigate the molecular basis for the phenotypic differences observed between MV vaccine strains and recently isolated wild-type MV strains. The former downregulate CD46, the putative cellular rec...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Lecouturier, V, Fayolle, J, Caballero, M, Carabaña, J, Celma, M L, Fernandez-Muñoz, R, Wild, T F, Buckland, R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190349/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8676439/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.7.4200-4204.1996
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