Identification of two amino acids in the hemagglutinin glycoprotein of measles virus (MV) that govern hemadsorption, HeLa cell fusion, and CD46 downregulation: phenotypic markers that differentiate vaccine and wild-type MV strains.

We have used site-directed mutagenesis of the hemagglutinin (H) glycoprotein of measles virus (MV) to investigate the molecular basis for the phenotypic differences observed between MV vaccine strains and recently isolated wild-type MV strains. The former downregulate CD46, the putative cellular rec...

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Main Authors: Lecouturier, V, Fayolle, J, Caballero, M, Carabaña, J, Celma, M L, Fernandez-Muñoz, R, Wild, T F, Buckland, R
Formato: Artigo
Idioma:Inglês
Publicado: 1996
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC190349/
https://ncbi.nlm.nih.gov/pubmed/8676439
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