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Identification of two amino acids in the hemagglutinin glycoprotein of measles virus (MV) that govern hemadsorption, HeLa cell fusion, and CD46 downregulation: phenotypic markers that differentiate vaccine and wild-type MV strains.

We have used site-directed mutagenesis of the hemagglutinin (H) glycoprotein of measles virus (MV) to investigate the molecular basis for the phenotypic differences observed between MV vaccine strains and recently isolated wild-type MV strains. The former downregulate CD46, the putative cellular rec...

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書誌詳細
主要な著者: Lecouturier, V, Fayolle, J, Caballero, M, Carabaña, J, Celma, M L, Fernandez-Muñoz, R, Wild, T F, Buckland, R
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC190349/
https://ncbi.nlm.nih.gov/pubmed/8676439
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