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Mycolic acid synthesis: a target for ethionamide in mycobacteria?

Striking structural analogies exist between the two specific antimycobacterial drugs ethionamide (ETH) and isoniazid (INH), and they share several inhibitory properties in susceptible species of mycobacteria. The effect of ETH on mycolic acid synthesis was studied in whole cells and in cell extracts...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Quémard, A, Lanéelle, G, Lacave, C
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190338/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1416831/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.6.1316
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