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Mycolic acid synthesis: a target for ethionamide in mycobacteria?

Striking structural analogies exist between the two specific antimycobacterial drugs ethionamide (ETH) and isoniazid (INH), and they share several inhibitory properties in susceptible species of mycobacteria. The effect of ETH on mycolic acid synthesis was studied in whole cells and in cell extracts...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Quémard, A, Lanéelle, G, Lacave, C
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1992
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190338/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1416831/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.6.1316
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