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Mycolic acid synthesis: a target for ethionamide in mycobacteria?

Striking structural analogies exist between the two specific antimycobacterial drugs ethionamide (ETH) and isoniazid (INH), and they share several inhibitory properties in susceptible species of mycobacteria. The effect of ETH on mycolic acid synthesis was studied in whole cells and in cell extracts...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Quémard, A, Lanéelle, G, Lacave, C
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190338/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1416831/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.6.1316
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