Genetic analysis of polyomavirus large T nuclear localization: nuclear localization is required for productive association with pRb family members.
Polyomavirus large T antigen (LT) is a multifunctional nuclear protein. LT has two nuclear localization signals (NLS2), one spanning residues 189 to 195 (NLS1) and another spanning residues 280 to 286 (NLS2). Site-directed mutagenesis showed that each signal contains at least two critical residues....
Guardat en:
| Publicat a: | J Virol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190233/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8648692/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.6.3581-3588.1996 |
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