An N-terminal deletion mutant of simian virus 40 (SV40) large T antigen oligomerizes incorrectly on SV40 DNA but retains the ability to bind to DNA polymerase alpha and replicate SV40 DNA in vitro.

A peptide encompassing the N-terminal 82 amino acids of simian virus 40 (SV40) large T antigen was previously shown to bind to the large subunit of DNA polymerase alpha-primase (I. Dornreiter, A. Höss, A. K. Arthur, and E. Fanning, EMBO J. 9:3329-3336, 1990). We report here that a mutant T antigen,...

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Bibliografische gegevens
Hoofdauteurs: Weisshart, K, Bradley, M K, Weiner, B M, Schneider, C, Moarefi, I, Fanning, E, Arthur, A K
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC190225/
https://ncbi.nlm.nih.gov/pubmed/8648684
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