In vivo sequence diversity of the protease of human immunodeficiency virus type 1: presence of protease inhibitor-resistant variants in untreated subjects.

We have evaluated the sequence diversity of the protease human immunodeficiency virus type 1 in vivo. Our analysis of 246 protease coding domain sequences obtained from 12 subjects indicates that amino acid substitutions predicted to give rise to protease inhibitor resistance may be present in patie...

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Hlavní autoři: Lech, W J, Wang, G, Yang, Y L, Chee, Y, Dorman, K, McCrae, D, Lazzeroni, L C, Erickson, J W, Sinsheimer, J S, Kaplan, A H
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC190036/
https://ncbi.nlm.nih.gov/pubmed/8627733
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