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N-Terminal Mutants of Herpes Simplex Virus Type 2 gH Are Transported without gL but Require gL for Function

Glycoprotein H (gH) is conserved among all herpesviruses and is essential for virus entry and cell fusion along with gL, gB, and, in most alphaherpesviruses, gD. Within the gH/gL heterodimer, it is thought that gH accounts for the fusion function and gL acts as a chaperone for the folding and transp...

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Autors principals: Cairns, Tina M., Friedman, Lisa S., Lou, Huan, Whitbeck, J. Charles, Shaner, Marie S., Cohen, Gary H., Eisenberg, Roselyn J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900195/
https://ncbi.nlm.nih.gov/pubmed/17344290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00097-07
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