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Induction of Mutations in Drosophila melanogaster gypsy Retroelements by Modulation of Intracellular Deoxynucleoside Triphosphate Pools In Vivo

The retroviral mutation rate is susceptible to a number of variables, including the balance between intracellular deoxynucleoside triphosphate (dNTP) pools. While this follows from tissue culture studies, the issue has never been addressed directly in vivo. To explore this question in a tractable ex...

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Autori principali: Terzian, Christophe, Henry, Michel, Meyerhans, Andreas, Wain-Hobson, Simon, Vartanian, Jean-Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900171/
https://ncbi.nlm.nih.gov/pubmed/17301142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02558-06
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